Boehringer Ingelheim BioXcellence™ applies state-of-the-art technologies to the development of biopharmaceuticals. As an experienced contract manufacturer, we offer sophisticated pre-formulation, formulation, and pharmaceutical process development. Our dosage form portfolio ranges from solutions, highly concentrated liquid formulations (HCLF), suspensions, lyophilized or spray-dried powders to inhalable presentations combined with state-of-the art proprietary application systems.
For certain therapeutic indications, a subcutaneous application is needed. In cases when the applied doses are high, such as for monoclonal antibodies, highly concentrated liquid protein formulations are required. With over 35 years of experience in the development and manufacturing of biopharmaceuticals, Boehringer Ingelheim BioXcellence™ offers proven methods to effectively and economically produce HCLFs. Our concepts include solubility tests, accelerated stress studies, and early integration of our formulation activities with our downstream process development.
Our services in contract manufacturing include the selection and optimization of primary packaging such as vials, pre-filled syringes and cartridges, as well as the development of application systems. We provide a comprehensive and flexible set of options to meet the specific needs of your biopharmaceutical molecule on its way to becoming a drug product.
Our fast-track development approach is both cost-efficient and effective: we offer the delivery of formulations and dosage forms suitable for toxicological studies and clinical Phase I studies within 15 months after start of development.
Profit from our Fill & Finish process and an excellent track record in biotechnology: high-end analytical science, our expertise in protein-containing pharmaceuticals and freeze-dried products warrant efficiency and quality in the development of appropriate and robust formulations.